What exactly are nanoparticles? What is meant by “exposure”? When do toxicologists speak of a risk? This and many more questions regarding research on safety aspects of nanomaterials are answered here: www.nanoobjects.info
Beginning of December 2017, the German Federal Environmental Agency (UBA) published a report entitled “Clarification of methodical questions regarding the investigation of nanomaterials in the environment: Development of a decision support tool for the investigation of nanomaterial’s environmental behaviour based on dispersion behaviour and dissolution in relation to various environmental parameters”. The final report describes the considerations, experimental approaches, and obtained results that build the basis for the new OECD Test Guideline. The report also contains a literature review of transformation reactions of nanomaterials in environmental media.
For an adequate and valid interpretation of data regarding the environmental fate and behaviour of nanomaterials it is essential to describe parameters like dissolution (rate), dispersibility and dispersion stability. The aim of the project was the development of a standardized test method to determine dispersibility and dispersion stability of nanomaterials in simulated environmental media as new OECD Test Guideline.
For this objective, both conceptual and experimental work was conducted and an international round robin was initiated and executed to validate the proposed test setup regarding reliability and reproducibility. Two comprehensive expert commenting rounds of the OECD Test Guideline program supported the refinement of the draft within this project.
The test method developed in this project was submitted to the OECD Test Guideline program by UBA and published by OECD in October 2017 as new “Test Guideline on dispersion stability of nanomaterials in simulated environmental media (OECD No. 318)”.
Original Publications:
OECD (2017). Test No. 318: Dispersion Stability of Nanomaterials in Simulated Environmental Media. OECD Publishing, Paris. DOI:10.1787/9789264284142-en
Umweltbundesamt (Dec 2017). Clarification of methodical questions regarding the investigation of nanomaterials in the environment: Development of a decision support tool for the investigation of nanomaterial’s environmental behaviour based on dispersion behaviour and dissolution in relation to various environmental parameters. Texte | 108/2017, ISSN 1862-4804. (PDF, 3.3 MB)
Information on the sponsorship programmes of the German Federal Ministry of Education and Research on nanotechnologies for humans and the environment.
A database with important and generally understandable aspects on health and environment of applied nanomaterials as well as facts on the safety of manufactured nanomaterials.
The chapters on release, exposure, uptake and behavior of nanomaterials in the human body and in the environment as well as the risk assessment will give you a first overview.
Thu Dec 05 @ 9:00AM - 03:00PM Advanced Materials - 1st Thematic Conference |
Mon Nov 16 @ 8:00AM - 05:00PM Nanosafe 2020 |